SCHEMBL3801326

SCHEMBL3801326

CCCc1cc(C)c(N)c(C)c1N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SKP2 Q13309 1/20 0.37
ALDH1A1 P00352 10/20 0.37
TSHR P16473 4/20 0.37
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 2/20 0.37
HTT P42858 1/20 0.37
HSD17B10 Q99714 3/20 0.35
CYP1A2 P05177 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP7 P55210 1/20 0.35
HIF1A Q16665 1/20 0.35
NOS2 P35228 4/20 0.34
NOS3 P29474 2/20 0.34
NOS1 P29475 2/20 0.34
KDM4E B2RXH2 4/20 0.34
POLB P06746 3/20 0.33
ALDH1A2 O94788 1/20 0.33
ALDH2 P05091 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27671383 0.89 SKP2 (0.44) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL3797886 0.89 NOS2 (0.38) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL1333373 0.82 ALDH1A1 (0.52) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL31329205 0.82 ALDH1A1 (0.52) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL28147630 0.82 ALDH1A1 (0.32) SKP2ALDH1A1MAPTHTTHSD17B10
SCHEMBL3799895 0.81 NOS2 (0.40) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL5161523 0.78 ALDH1A1 (0.37) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL2317711 0.77 NOS2 (0.40) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL2724396 0.76 NOS2 (0.37) SKP2ALDH1A1TSHRTDP1TP53
SCHEMBL31510796 0.76 ALDH1A1 (0.33) SKP2ALDH1A1TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7674193-B2 Golf ball SRI SPORTS LIMITED (JP) 2010-03-09 US disclosed
US-7208533-B2 Cover composition for golf ball SRI SPORTS LIMITED (JP) 2007-04-24 US disclosed
US-20050187336-A1 Cover composition for golf ball SUMITOMO RUBBER INDUSTRIES, LTD. 2005-08-25 US disclosed
US-6933336-B2 Golf ball SRI SPORTS LIMITED (JP) 2005-08-23 US disclosed
US-20040029652-A1 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2004-02-12 US disclosed
US-20030232934-A1 Golf ball SRI SPORTS LIMITED (JP) 2003-12-18 US disclosed