Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 4/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3688741 | 1.00 | ZDHHC20 (0.36) | ZDHHC20ZDHHC2TSHRCES2EP300 | |
| SCHEMBL1853325 | 0.98 | ZDHHC20 (0.33) | ZDHHC20ZDHHC2TSHRCES2EP300 | |
| SCHEMBL23879202 | 0.93 | CA12 (0.33) | TSHRCES1 | |
| SCHEMBL1085830 | 0.93 | CA12 (0.33) | TSHRCES1 | |
| SCHEMBL11026994 | 0.86 | — | — | |
| SCHEMBL28019376 | 0.84 | DNM1 (0.40) | ZDHHC20ZDHHC2TSHREP300DNM1 | |
| SCHEMBL28061988 | 0.81 | CA12 (0.32) | EP300CES1 | |
| SCHEMBL17157534 | 0.81 | — | — | |
| SCHEMBL28048587 | 0.79 | CA12 (0.35) | TSHRCES1 | |
| SCHEMBL515572 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7786208-B2 | Modified natural rubber masterbatch and method for producing the same as well as rubber composition and tire | BRIDGESTONE CORPORATION (JP) | 2010-08-31 | — | — | US | disclosed |
| US-20080125534-A1 | Modified Natural Rubber Masterbatch And Method For Producing The Same As Well As Rubber Composition And Tire | BRIDGESTONE CORPORATION (JP) | 2008-05-29 | — | — | US | disclosed |