Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.63 |
| ▸ | RARG | P13631 | 8/20 | 0.63 |
| ▸ | RARA | P10276 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.63 |
| ▸ | GOT1 | P17174 | 1/20 | 0.63 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803050 | 1.00 | RARB (0.63) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL979218 | 0.91 | RARB (0.72) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL980744 | 0.91 | RARB (0.72) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8765807 | 0.90 | RARB (0.62) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7920651 | 0.90 | RARB (0.54) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL641921 | 0.85 | RARB (0.81) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL30698054 | 0.85 | RARB (0.81) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL25230655 | 0.84 | IKBKB (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL30428692 | 0.84 | IKBKB (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7077350 | 0.84 | RARB (0.61) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168241-A1 | TREATMENT OF ACNE DISEASE STATES, NOTABLY ACNE VULGARIS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-07-01 | — | — | US | disclosed |
| EP-2152259-A1 | USE OF A NAPHTOIC ACID DERIVATIVE IN COMBINATION WITH RED AND/OR BLUE LIGHT FOR TREATING ACNE VULGARIS | Galderma Research & Development (FR) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008135548-A1 | USE OF A NAPHTOIC ACID DERIVATIVE IN COMBINATION WITH RED AND/OR BLUE LIGHT FOR TREATING ACNE VULGARIS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168241-A1 | TREATMENT OF ACNE DISEASE STATES, NOTABLY ACNE VULGARIS | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.