Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.72 |
| ▸ | RARG | P13631 | 8/20 | 0.72 |
| ▸ | RARA | P10276 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | PGR | P06401 | 1/20 | 0.72 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.72 |
| ▸ | GOT1 | P17174 | 1/20 | 0.72 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980744 | 1.00 | RARB (0.72) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL3803050 | 0.91 | RARB (0.63) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL3801401 | 0.91 | RARB (0.63) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7521122 | 0.90 | MEN1 (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL5081246 | 0.90 | RARB (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9133374 | 0.90 | RARA (0.55) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8767123 | 0.89 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9133769 | 0.88 | RARA (0.54) | RARBRARGRARAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8765869 | 0.88 | RARG (0.69) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8766163 | 0.85 | RARG (0.74) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020068665-A1 | USE OF COLLAGEN BINDING DOMAINS TO DELIVER PRODUCTS TO SKIN | FABIUS BIOTECHNOLOGY (US) | 2020-04-02 | — | — | WO | claimed |
| EP-2224908-B1 | COMPOSITIONS CONTAINING AT LEAST ONE NAPHTHOIC ACID DERIVATIVE, BENZOYL PEROXIDE AND AT LEAST ONE FILM-FORMING AGENT, METHODS FOR PREPARING SAME AND USES THEREOF | GALDERMA RES & DEV (FR) | 2017-11-01 | — | — | EP | claimed |
| EP-2364692-B1 | Compositions including at least one derivative of naphtoic acid, benzoyl peroxide and at least one film-forming agent, methods for preparing same and uses thereof | GALDERMA RES & DEV (FR) | 2017-10-25 | — | — | EP | claimed |
| US-20150342920-A1 | DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE RETINOID COMPOUND, AN ANTI-IRRITANT COMPOUND AND BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-12-03 | — | — | US | claimed |
| EP-2416768-B1 | COMPOSITIONS COMPRISING AT LEAST ONE COMPLEX COMPOSED OF A DERIVATIVE OF NAPHTHOIC ACID AND OF AT LEAST ONE CYCLODEXTRIN AND USES THEREOF | GALDERMA RES & DEV (FR) | 2015-10-07 | — | — | EP | claimed |
| US-20150216834-A1 | PHARMACEUTICAL/COSMETIC, E.G., ANTI-ACNE COMPOSITIONS COMPRISING AT LEAST ONE NAPHTOIC ACID COMPOUND, BENZOYL PEROXIDE AND AT LEAST ONE FILM-FORMING AGENT | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-08-06 | — | — | US | claimed |
| US-20150098918-A1 | CREAM GELS COMPRISING AT LEAST ONE RETINOID AND BENZOYL PEROXIDE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-04-09 | — | — | US | claimed |
| EP-2167062-B1 | Compositions and uses comprising a retinoid compound, an anti-irritant compound and benzoyl peroxide in acne | GALDERMA RES & DEV (FR) | 2015-02-18 | — | — | EP | claimed |
| US-8937098-B2 | Dermatological compositions comprising at least one naphthoic acid compound and at least one film-forming agent and treatment of keratinization disorders therewith | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2015-01-20 | — | — | US | claimed |
| EP-2029133-B1 | COMPOSITIONS COMPRISING AT LEAST ONE NAPHTHOIC ACID DERIVATIVE AND AT LEAST ONE FILM-FORMING AGENT, METHODS FOR PREPARING SAME, AND USES THEREOF | GALDERMA RES & DEV (FR) | 2014-11-05 | — | — | EP | claimed |
| US-20090247630-A1 | DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE NAPHTHOIC ACID COMPOUND AND AT LEAST ONE FILM-FORMING AGENT AND TREATMENT OF KERATINIZATION DISORDERS THEREWITH | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-10-01 | — | — | US | claimed |
| US-20090191245-A1 | REDUCED-IRRITANT DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE NAPHTHOIC ACID COMPOUND AND BENZOYL PEROXIDE AND TREATMENT OF KERATINIZATION DISORDERS THEREWITH | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-07-30 | — | — | US | claimed |
| US-20090098219-A1 | Cosmetic/pharmaceutical compositions comprising retinoids and anti-irritants and treatment of keratinization disorders therewith | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-04-16 | — | — | US | claimed |
| US-20090012172-A1 | Cosmetic/pharmaceutical compositions comprising retinoids and anti-irritants and treatment of keratinization disorders therewith | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2009-01-08 | — | — | US | claimed |
| WO-2008152064-A1 | COMPOSITIONS AND USES COMPRISING A RETINOID COMPOUND, AN ANTI-IRRITANT COMPOUND AND BENZOYL PEROXIDE IN ACNE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-12-18 | — | — | WO | claimed |
| WO-2008152065-A1 | COMPOSITION AND USES OF A RETINOID, AN ANTI-IRRITANT COMPOUND AND BENZOYL PEROXIDE, IN ACNE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-12-18 | — | — | WO | claimed |
| US-20080253986-A1 | Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2008-10-16 | — | — | US | claimed |
| EP-1933827-A2 | COMPOSITION COMPRISING AT LEAST ONE NAPHTHOIC ACID DERIVATIVE AND AT LEAST ONE COMPOUND OF POLYURETHANE POLYMER TYPE OR DERIVATIVES THEREOF, PREPARATION PROCESSES THEREFOR AND USES THEREOF | Galderma Research & Development, S.N.C. (FR) | 2008-06-25 | — | — | EP | claimed |
| WO-2007031883-A2 | COMPOSITION COMPRISING AT LEAST ONE NAPHTHOIC ACID DERIVATIVE AND AT LEAST ONE COMPOUND OF POLYURETHANE POLYMER TYPE OR DERIVATIVES THEREOF, PREPARATION PROCESSES THEREFOR AND USES THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2007-03-22 | — | — | WO | claimed |
| EP-0199636-B1 | BENZONAPHTHALENIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PHARMACY AND COSMETICS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. Groupement d'Intérêt Economique dit: (FR) | 1989-02-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216834-A1 | PHARMACEUTICAL/COSMETIC, E.G., ANTI-ACNE COMPOSITIONS COMPRISING AT LEAST ONE NAPHTOIC ACID COMPOUND, BENZOYL PEROXIDE AND AT LEAST ONE FILM-FORMING AGENT | PAOX, CUTA, ACOX1 | RARB 155/4885RARG 114/4885RARA 78/4885 |
| US-20090247630-A1 | DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE NAPHTHOIC ACID COMPOUND AND AT LEAST ONE FILM-FORMING AGENT AND TREATMENT OF KERATINIZATION DISORDERS THEREWITH | CUTA, NOTUM, KRT18 | RARB 25/4885RARG 29/4885RARA 5/4885 |
| US-20090191245-A1 | REDUCED-IRRITANT DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE NAPHTHOIC ACID COMPOUND AND BENZOYL PEROXIDE AND TREATMENT OF KERATINIZATION DISORDERS THEREWITH | CUTA, KRT18, RARA | RARB 6/4885RARG 9/4885RARA 3/4885 |
| US-20080253986-A1 | Cosmetic/dermatological compositions comprising naphthoic acid compounds and polyurethane polymers | CUTA, NACA, PUF60 | RARB 136/4885RARG 126/4885RARA 58/4885 |
| US-20090012172-A1 | Cosmetic/pharmaceutical compositions comprising retinoids and anti-irritants and treatment of keratinization disorders therewith | KRT18, RARA, RARB | RARB 3/4885RARG 4/4885RARA 2/4885 |
| US-20090098219-A1 | Cosmetic/pharmaceutical compositions comprising retinoids and anti-irritants and treatment of keratinization disorders therewith | RARA, RARB, RARG | RARB 2/4885RARG 3/4885RARA 1/4885 |
| US-20150342920-A1 | DERMATOLOGICAL COMPOSITIONS COMPRISING AT LEAST ONE RETINOID COMPOUND, AN ANTI-IRRITANT COMPOUND AND BENZOYL PEROXIDE | RARB, RARA, RARG | RARB 1/4885RARG 3/4885RARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.