Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 3/20 | 0.66 |
| ▸ | TSHR | P16473 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94507 | 0.85 | CYP3A4 (0.43) | CASP1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL29835021 | 0.85 | CYP3A4 (0.43) | CASP1TSHRCYP3A4ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1154738 | 0.83 | CYP3A4 (0.41) | CASP1TSHRCYP3A4ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL22612489 | 0.81 | CYP3A4 (0.40) | CASP1TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL93860 | 0.81 | — | — | |
| SCHEMBL4869221 | 0.81 | CASP1 (1.00) | CASP1TSHRCYP3A4PDE10ACA1 | |
| SCHEMBL29670126 | 0.81 | — | — | |
| 3-Aminophenol SCHEMBL27484047 | 0.80 | ALDH1A1 (0.55) | CASP1TSHRCYP3A4PDE10ACA1 | |
| Dimethylamine SCHEMBL9021118 | 0.75 | CASP1 (0.86) | CASP1TSHRCYP3A4PDE10ACA1 | |
| SCHEMBL3176011 | 0.75 | ALDH1A1 (0.44) | CASP1TSHRCYP3A4CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155152-A2 | COLOURING COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND EXHIBITING AN ACIDIC PH | L'Oreal (FR) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008138845-A2 | COLOURING COMPOSITION COMPRISING AN AMINOPYRAZOLOPYRIDINE OXIDATION BASE AND EXHIBITING AN ACIDIC PH | L'OREAL (FR) | 2008-11-20 | — | — | WO | disclosed |