SCHEMBL380152

SCHEMBL380152

CC(C)(C)OC(=O)c1ccc(N)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA9 Q16790 1/20 0.57
CA14 Q9ULX7 1/20 0.57
LMNA P02545 2/20 0.55
CYP1A2 P05177 2/20 0.55
CYP3A4 P08684 2/20 0.55
MAOA P21397 2/20 0.55
TSHR P16473 2/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
PDE4D Q08499 1/20 0.49
ADRB2 P07550 2/20 0.47
ADRB1 P08588 2/20 0.47
ADRB3 P13945 2/20 0.47
NR1H4 Q96RI1 1/20 0.47
PHLPP2 Q6ZVD8 1/20 0.47
NPC1 O15118 1/20 0.46
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL28278848 0.98 CA12 (0.56) CA12CA1CA2CA9CA14
Nitrogen SCHEMBL27824368 0.96 CA12 (0.54) CA12CA1CA2CA9CA14
Acetic Acid SCHEMBL5239675 0.94 CA12 (0.53) CA12CA1CA2CA9CA14
SCHEMBL8097425 0.94 CA12 (0.66) CA12CA1CA2CA9CA14
Formic Acid Methyl Ester SCHEMBL28278877 0.89 CA12 (0.49) CA12CA1CA2CA9CA14
Hydrazine SCHEMBL10771056 0.89 CA12 (0.62) CA12CA1CA2CA9CA14
SCHEMBL109451 0.89 CA1 (0.61) CA12CA1CA2CA9CA14
SCHEMBL28625201 0.85 LMNA (0.49) CA12CA1CA2CA9CA14
SCHEMBL21015615 0.83 CA1 (0.57) CA12CA1CA2CA9CA14
SCHEMBL27366401 0.83 CA12 (0.57) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
CN-115466341-B Ashless dispersant and preparation method thereof 新乡市瑞丰新材料股份有限公司 2024-12-20 CN claimed
CN-118067670-A Paper-based sensor and preparation method and application thereof 浙江工业大学 2024-05-24 CN claimed
CN-114920920-B Process for the preparation of sterically hindered amine-terminated polyethers and products derived from said sterically hindered amine-terminated polyethers 山西省建筑科学研究院集团有限公司 2023-10-10 CN claimed
CN-112010856-B Folic acid telescoping process method by utilizing microchannel reaction 威海中腾医药科技有限公司 2023-05-16 CN claimed
CN-116103349-A Enzyme-catalyzed folic acid green synthesis method 苏州伯凯医药科技有限公司 2023-05-12 CN claimed
CN-115466341-A Ashless dispersant and preparation method thereof 新乡市瑞丰新材料股份有限公司 2022-12-13 CN claimed
CN-111747957-B Multi-target antitumor quinolizidine derivatives, and preparation method and application thereof 天津市医药科学研究所 2022-12-09 CN claimed
CN-114920920-A Process for the preparation of sterically hindered amine-terminated polyethers and process for the preparation of products derived therefrom 山西省建筑科学研究院有限公司 2022-08-19 CN claimed
CN-108794474-B Evodiamine derivative with multi-target antitumor activity and preparation method and application thereof 中国人民解放军第二军医大学 2022-03-18 CN claimed
CN-112010856-A Telescoping process method for preparing folic acid by using microchannel reaction 威海中腾医药科技有限公司 2020-12-01 CN claimed
CN-110105362-B Safe and green folic acid synthesis method catalyzed by heteropoly acid 威海中腾医药科技有限公司 2020-10-23 CN claimed
CN-111747957-A Multi-target antitumor quinolizidine derivatives, and preparation method and application thereof 天津市医药科学研究所 2020-10-09 CN claimed
CN-108794474-A Rutaecarpin derivative and its preparation method and application with multiple target point antitumor activity 中国人民解放军第二军医大学 2018-11-13 CN claimed
US-8334383-B2 Regioselective preparation of substituted pyrimidines BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-12-18 US claimed
WO-2026107406-A1 p53 HETEROBIFUNCTIONAL CONJUGATES AND USES THEREOF Design Therapeutics, Inc. (US) 2026-05-21 WO disclosed
CN-116496219-B Six-membered and five-membered heterocyclic compound, and pharmaceutical composition and application thereof 东南大学 2026-05-15 CN disclosed
US-4600580-A Novel enzyme derivatives BEECHAM GROUP P.L.C. (GB) 1986-07-15 US disclosed
EP-0155388-A2 Enzyme-protein conjugate, process for its preparation and pharmaceutical use thereof BEECHAM GROUP PLC (GB) 1985-09-25 EP disclosed
US-4234600-A Combating arthropods with N-benzoyl-N'-tert.-alkoxycarbonylphenyl-(thio) ureas BAYER AKTIENGESELLSCHAFT (DE) 1980-11-18 US disclosed