Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26999253 | 0.76 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL23372981 | 0.76 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL20587771 | 0.76 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL24406713 | 0.76 | MEN1 (0.41) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL3797300 | 0.71 | HPGD (0.38) | MEN1KMT2ANPC1RAB9AHPGD | |
| SCHEMBL12352995 | 0.71 | HPGD (0.33) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL12353015 | 0.70 | GSK3A (0.35) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL12353140 | 0.68 | GSK3A (0.34) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5653503 | 0.68 | HPGD (0.36) | MEN1KMT2AHPGDTSHR | |
| SCHEMBL12353317 | 0.68 | GSK3A (0.34) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| US-7829044-B2 | Phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-1496063-B1 | EXTRACTION PROCESS FOR RARE EARTH METAL IONS USING A PHOSPHONAMIDE COMPOUND | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-08-19 | — | — | EP | disclosed |
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-05-19 | — | — | US | disclosed |
| EP-1496063-A1 | NOVEL PHOSPHONAMIDES, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Japan Science and Technology Agency (JP) | 2005-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107599-A1 | Novel phosphonamides, process for producing the same, and use thereof | PHYKPL, CDKL1, MASTL | MEN1 619/4885KMT2A 3902/4885NPC1 3995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.