SCHEMBL3801957

SCHEMBL3801957

CC(C)(CC=Cc1ccccc1)OC=Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.43
HTR2A P28223 3/20 0.41
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
PAM P19021 1/20 0.39
MMP1 P03956 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
RAB9A P51151 1/20 0.38
RELA Q04206 1/20 0.37
SIGMAR1 Q99720 2/20 0.37
TRPA1 O75762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3783785 0.81 RELA (0.43) IDO1KMT2AMEN1RAB9ARELA
SCHEMBL3626140 0.80 IDO1 (0.44) IDO1HTR2AKMT2AMEN1PAM
SCHEMBL11662452 0.79 RELA (0.44) IDO1HTR2AMMP1MMP9MMP13
Boric Acid SCHEMBL28619442 0.77 KMT2A (0.36) IDO1HTR2AKMT2AMEN1PAM
SCHEMBL23919129 0.77 HTR2A (0.48) IDO1HTR2AKMT2AMEN1PAM
SCHEMBL11048026 0.77 HTR2A (0.48) IDO1HTR2AKMT2AMEN1PAM
SCHEMBL187273 0.77 MAOB (0.44) KMT2AMEN1RELATRPA1
SCHEMBL7770617 0.77 MAOB (0.44) KMT2AMEN1RELATRPA1
SCHEMBL5348553 0.75 EGFR (0.42) RELA
SCHEMBL6419016 0.73 IDO1 (0.42) IDO1HTR2AKMT2AMEN1PAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8975327-B2 Controlling morphology of block copolymers DOW CORNING CORPORATION (US) 2015-03-10 US disclosed
US-20150064115-A1 NEUROPHILIC NANOPARTICLES UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2015-03-05 US disclosed
EP-2643413-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS Dow Corning Corporation (US) 2013-10-02 EP disclosed
US-20130231438-A1 Controlling Morphology of Block Copolymers DOW CORNING CORPORATION (US) 2013-09-05 US disclosed
WO-2012071330-A1 CONTROLLING MORPHOLOGY OF BLOCK COPOLYMERS DOW CORNING CORPORATION (US) 2012-05-31 WO disclosed
US-7846412-B2 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis EMORY UNIVERSITY (US) 2010-12-07 US disclosed
WO-2008137733-A2 MICELLAR STRUCTURES, METHODS OF MAKING MICELLAR STRUCTURES, METHODS OF IMAGING, AND METHODS OF DELIVERING AGENTS EMORY UNIVERSITY (US) 2008-11-13 WO disclosed
WO-2008116044-A1 SEMICONDUCTOR QUANTUM DOTS FOR EFEICIENT DELIVERY AND INTRACELLULAR IMAGING OF SIRNA EMORY UNIVERSITY (US) 2008-09-25 WO disclosed
EP-1696784-A2 BIOCONJUGATED NANOSTRUCTURES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF Emory University (US) 2006-09-06 EP disclosed
WO-2005065081-A2 BIOCONJUGATED NANOSTRUCTURES, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF EMORY UNIVERSITY (US) 2005-07-21 WO disclosed
US-20050136258-A1 Nanoparticle fluorescent probes comprised of quantum dot and hydrophobic protection structure including capping ligand and amphiphilic copolymer; biocompatibility; multiplexed imaging and detection of genes and proteins in single living cells; cancer diagnosis NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-23 US disclosed