Known targets — ChEMBL curated mechanism
S1PR1S1PR2S1PR3S1PR4S1PR5rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 known ✓ | Q99500 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.55 |
| ▸ | CA2 | P00918 | 10/20 | 0.55 |
| ▸ | CA9 | Q16790 | 8/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.55 |
| ▸ | CA7 | P43166 | 3/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6157369 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Benzene SCHEMBL11677157 | 1.00 | CA1 (0.55) | CA1CA2CA9CA12CA7 | |
| Benzene SCHEMBL7806416 | 0.98 | CA1 (0.53) | CA1CA2CA9CA12CA7 | |
| Benzene SCHEMBL10842409 | 0.98 | CA1 (0.53) | CA1CA2CA9CA12CA7 | |
| Benzene SCHEMBL16294960 | 0.98 | CA1 (0.53) | CA1CA2CA9CA12CA7 | |
| Benzene SCHEMBL4610944 | 0.96 | CA1 (0.52) | CA1CA2CA9CA12CA7 | |
| SCHEMBL374800 | 0.94 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| Octadecyl Sulfate SCHEMBL41459 | 0.94 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22283885 | 0.94 | CA1 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL10583495 | 0.94 | CA1 (0.61) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119956435-A | Simple production method of foam metal | 广州三孚新材料科技股份有限公司 | 2025-05-09 | — | — | CN | claimed |
| CN-119932656-A | Large-scale preparation method of ultrathin foam copper | 广州三孚新材料科技股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| US-12057585-B2 | Conductive composition for secondary battery | GRST INTERNATIONAL LIMITED (CN) | 2024-08-06 | — | — | US | claimed |
| US-20230343963-A1 | CONDUCTIVE COMPOSITION FOR SECONDARY BATTERY | GRST INTERNATIONAL LIMITED (HK) | 2023-10-26 | — | — | US | claimed |
| EP-4094315-A1 | CONDUCTIVE COMPOSITION FOR SECONDARY BATTERY | GRST International Limited (CN) | 2022-11-30 | — | — | EP | claimed |
| EP-3865112-B1 | METHOD FOR MAKING COMPOSITION FOR ENAMEL REGENERATION | UNIV XIAN SCI & TECHNOLOGY (CN) | 2022-05-11 | — | — | EP | claimed |
| WO-2021254155-A1 | CONDUCTIVE COMPOSITION FOR SECONDARY BATTERY | GUANGDONG HAOZHI TECHNOLOGY CO. LIMITED (CN) | 2021-12-23 | — | — | WO | claimed |
| US-20210315209-A1 | AEROSOL AGENT FOR INSECT PEST CONTROL AND INSECT PEST CONTROL METHOD | DAINIHON JOCHUGIKU CO., LTD. (JP) | 2021-10-14 | — | — | US | claimed |
| CN-112584705-A | Aerosol agent for controlling insect pests and method for controlling insect pests | 大日本除虫菊株式会社 | 2021-03-30 | — | — | CN | claimed |
| CN-111172521-A | Method for metallizing surface of liquid crystal high molecular polymer | 广州三孚新材料科技股份有限公司 | 2020-05-19 | — | — | CN | claimed |
| US-4904466-A | Polymers which form gels at low concentrations in water | BASF CORPORATION (US) | 1990-02-27 | — | — | US | claimed |
| US-20250167196-A1 | A Conductive Composition | GRST SINGAPORE PTE. LTD. (SG) | 2025-05-22 | — | — | US | disclosed |
| CN-119956435-A | Simple production method of foam metal | 广州三孚新材料科技股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-119932656-A | Large-scale preparation method of ultrathin foam copper | 广州三孚新材料科技股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| EP-4457881-A1 | A CONDUCTIVE COMPOSITION | GRST International Limited (HK) | 2024-11-06 | — | — | EP | disclosed |
| WO-1994019000-A1 | MICROEMULSIONS CONTAINING PHARMACEUTICAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1994-09-01 | — | — | WO | disclosed |
| US-4904466-A | Polymers which form gels at low concentrations in water | BASF CORPORATION (US) | 1990-02-27 | — | — | US | disclosed |
| US-4810503-A | POLYETHER CAPPED WITH ALPHA-OLEFIN EPOXIDE HAVING 20 TO 45 CARBONS | BASF CORPORATION (US) | 1989-03-07 | — | — | US | disclosed |
| US-4592875-A | Ratio of oxyethylene to oxyalkylene groups | ATLANTIC RICHFIELD COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| US-4169817-A | PROTEASE | MIDWEST BIOCHEMICAL CORPORATION (US) | 1979-10-02 | — | — | US | disclosed |