⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583498 | 0.82 | — | — | |
| SCHEMBL1972246 | 0.69 | — | — | |
| SCHEMBL498502 | 0.69 | — | — | |
| SCHEMBL566960 | 0.67 | — | — | |
| SCHEMBL2846569 | 0.66 | — | — | |
| SCHEMBL8566840 | 0.64 | — | — | |
| SCHEMBL3938140 | 0.63 | — | — | |
| SCHEMBL4351236 | 0.62 | — | — | |
| SCHEMBL1285258 | 0.61 | — | — | |
| SCHEMBL12693419 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 479 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3109254-B1 | CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE | UNIV OSAKA (JP) | 2018-04-11 | — | — | EP | claimed |
| US-4496745-A | Epoxycarbacyclin derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | claimed |
| WO-2024101446-A1 | MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME | ルクサナバイオテク株式会社 | 2024-05-16 | — | — | WO | disclosed |
| CN-112513062-B | Oligonucleotide-containing small cell lung cancer therapeutic agent | 国立大学法人大阪大学 | 2024-05-10 | — | — | CN | disclosed |
| US-20240148775-A1 | OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING | OSAKA UNIVERSITY (JP) | 2024-05-09 | — | — | US | disclosed |
| EP-4357335-A1 | AZABICYCLO[3.1.0]HEXANE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2024-04-24 | — | — | EP | disclosed |
| CN-117480153-A | Azabicyclo [3.1.0] hexane compounds | 大塚制药株式会社 | 2024-01-30 | — | — | CN | disclosed |
| US-11866705-B2 | Small cell lung cancer therapeutic agent containing oligonucleotide | Osaka Univerity (JP) | 2024-01-09 | — | — | US | disclosed |
| EP-4299744-A1 | OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING | OSAKA UNIVERSITY (JP) | 2024-01-03 | — | — | EP | disclosed |
| US-11840530-B2 | Selective EP4 receptor antagonistic substance for treatment of cancer | ASKAT INC. (JP) | 2023-12-12 | — | — | US | disclosed |
| WO-2023224108-A1 | NUCLEOSIDE DERIVATIVE AND USE THEREOF | 株式会社GF・Mille | 2023-11-23 | — | — | WO | disclosed |
| EP-0200522-B1 | PROCESS FOR PREPARING GRISEOLIC ACID DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1990-10-31 | — | — | EP | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0332387-A1 | Triazole derivatives, their preparation and their use as fungicides | Sankyo Company Limited (JP) | 1989-09-13 | — | — | EP | disclosed |
| EP-0319316-A2 | Griseolic acid monoesters, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4783532-A | Process for preparing griseolic acid derivatives | SANKYO COMPANY LIMITED (JP) | 1988-11-08 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |
| EP-0200522-A2 | Process for preparing griseolic acid derivatives | SANKYO COMPANY LIMITED (JP) | 1986-11-05 | — | — | EP | disclosed |
| US-4496745-A | Epoxycarbacyclin derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |