Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.38 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2550532 | 0.94 | TSHR (0.50) | TSHRACLYPAMDGKALMNA | |
| SCHEMBL11662512 | 0.90 | TSHR (0.50) | TSHRACLYPAMDGKALMNA | |
| SCHEMBL245767 | 0.88 | TSHR (0.50) | TSHRPAMDGKALMNAALDH1A1 | |
| SCHEMBL11661902 | 0.87 | TSHR (0.53) | TSHRPAMDGKALMNAGPR84 | |
| SCHEMBL27546692 | 0.85 | ACLY (0.49) | TSHRACLYACACBACACAPPARA | |
| Bicarbonate SCHEMBL3894794 | 0.84 | TSHR (0.62) | TSHRPAMDGKALMNAGPR84 | |
| SCHEMBL10543145 | 0.84 | TSHR (0.67) | TSHRPAMDGKALMNAGPR84 | |
| SCHEMBL680310 | 0.84 | TSHR (0.67) | TSHRPAMDGKALMNAGPR84 | |
| SCHEMBL7540354 | 0.84 | TSHR (0.67) | TSHRPAMDGKALMNAGPR84 | |
| SCHEMBL953501 | 0.84 | TSHR (0.67) | TSHRPAMDGKALMNAGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408331-A2 | COMPOSITION COMPRISING THE COMBINATION OF MADECASSOSIDE, OF AN ARGININE AND OF POLYSORBATE | L'Oréal (FR) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105951-A2 | COMPOSITION COMPRISING THE COMBINATION OF MADECASSOSIDE, OF AN ARGININE AND OF POLYSORBATE | L'OREAL (FR) | 2010-09-23 | — | — | WO | disclosed |