Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | CES1 | P23141 | 5/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28613977 | 0.94 | CA2 (0.39) | CA2TP53LMNAAKR1B1 | |
| SCHEMBL3803592 | 0.87 | CA2 (0.47) | CA2TP53LMNAFAAHCES1 | |
| SCHEMBL7714526 | 0.84 | CA2 (0.49) | CA2TP53LMNAFAAHCES1 | |
| SCHEMBL28613976 | 0.81 | CA2 (0.40) | CA2TP53LMNAFAAH | |
| SCHEMBL5872131 | 0.80 | TSHR (0.45) | CA2TP53LMNAFAAHCES1 | |
| SCHEMBL7432146 | 0.75 | CA2 (0.50) | CA2TP53FAAHCES1CES2 | |
| SCHEMBL8914952 | 0.74 | CA2 (0.50) | CA2FAAHCES1 | |
| SCHEMBL9635419 | 0.73 | CA2 (0.53) | CA2FAAHCES1CES2 | |
| SCHEMBL8364457 | 0.73 | CA2 (0.53) | CA2FAAHCES1CES2 | |
| SCHEMBL6578404 | 0.73 | CA2 (0.53) | CA2FAAHCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209496-A2 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009061854-A2 | MULTIFUNCTIONAL DEGRADABLE NANOPARTICLES WITH CONTROL OVER SIZE AND FUNCTIONALITIES | VANDERBILT UNIVERSITY (US) | 2009-05-14 | — | — | WO | disclosed |