SCHEMBL3806589

SCHEMBL3806589

CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)NCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 1/20 0.47
GPR84 Q9NQS5 7/20 0.46
PPARG P37231 7/20 0.46
PPARD Q03181 7/20 0.46
PPARA Q07869 7/20 0.46
HDAC11 Q96DB2 5/20 0.46
TSHR P16473 4/20 0.46
PTPN1 P18031 3/20 0.46
ALDH1A1 P00352 2/20 0.46
TLR2 O60603 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
FABP4 P15090 2/20 0.46
SLC22A6 Q4U2R8 1/20 0.46
SLC22A8 Q8TCC7 1/20 0.46
MEN1 O00255 1/20 0.46
ESR1 P03372 1/20 0.46
ALOX15 P16050 1/20 0.46
PDE4A P27815 1/20 0.46
KMT2A Q03164 1/20 0.46
PDE3A Q14432 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3716127 0.98 AKR1B1 (0.44) PLA2G2AGPR84PPARGPPARDPPARA
SCHEMBL28332779 0.96 PLA2G2A (0.44) PLA2G2AGPR84PPARGPPARDPPARA
SCHEMBL28328557 0.96 PLA2G2A (0.44) PLA2G2AGPR84PPARGPPARDPPARA
SCHEMBL29050098 0.87 FAAH (0.50) PLA2G2AGPR84PPARGPPARDPPARA
Spermine SCHEMBL7044349 0.84 PAOX (0.45) TSHRALDH1A1TDP1MEN1ALOX15
SCHEMBL28965535 0.82 FAAH (0.46) MEN1KMT2AKDM5APHF8KDM4C
SCHEMBL11686438 0.77 FFAR3 (0.40) PLA2G2AALDH1A1TDP1KDM5APHF8
SCHEMBL28250300 0.75 EPHX1 (0.44) GPR84PPARGPPARDPPARAHDAC11
Malonic Acid SCHEMBL3702459 0.74 KDM5A (0.61) GPR84PPARGPPARDPPARAHDAC11
Malonic Acid SCHEMBL3703381 0.74 KDM5A (0.61) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858117-B2 Amphoteric liposomes and their use NOVOSOM AG (DE) 2010-12-28 US claimed
CN-117693584-A Engineered meganucleases targeting the human mitochondrial genome 精密生物科学公司 2024-03-12 CN disclosed
CN-116057068-A Optimized engineered meganucleases with specificity for recognition sequences in hepatitis b virus genomes 精密生物科学公司 2023-05-02 CN disclosed
WO-2007065017-A2 OLIGONUCLEOTIDE CATIONIC LIPOSOMAL DELIVERY SYSTEM PRONAI THERAPEUTICS, INC. (US) 2007-06-07 WO disclosed
EP-1628636-A1 INJECTABLE LIPOSOMAL DEPOTS FOR DELIVERING ACTIVE INGREDIENTS Novosom AG (DE) 2006-03-01 EP disclosed
WO-2004100928-A1 INJECTABLE LIPOSOMAL DEPOTS FOR DELIVERING ACTIVE INGREDIENTS NOVOSOM AG (DE) 2004-11-25 WO disclosed