Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 1/20 | 0.38 |
| ▸ | SELE | P16581 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962866 | 0.86 | SELL (0.39) | SELLSELPSELENPC1HPGD | |
| SCHEMBL28401269 | 0.86 | HPGD (0.41) | SELLSELPSELENPC1HPGD | |
| SCHEMBL5677858 | 0.85 | SELL (0.40) | SELLSELPSELENPC1HPGD | |
| SCHEMBL2222707 | 0.82 | SELL (0.42) | SELLSELPSELENPC1HPGD | |
| SCHEMBL5586815 | 0.80 | ALOX15 (0.43) | SELLSELPSELEMAPK1HTT | |
| SCHEMBL1760472 | 0.80 | ALOX15 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL29668358 | 0.80 | ALOX15 (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL3676098 | 0.78 | BACE1 (0.37) | SELLSELPSELENPC1HPGD | |
| SCHEMBL27690770 | 0.78 | HPGD (0.35) | SELLSELPSELENPC1HPGD | |
| SCHEMBL2065679 | 0.76 | TRPA1 (0.48) | HPGDBACE1TRPA1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064861-A2 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED POLYMERS, COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-05-22 | — | — | WO | claimed |
| WO-2009064861-A2 | NITRIC OXIDE-RELEASING DIAZENIUMDIOLATED POLYMERS, COMPOSITIONS, MEDICAL DEVICES, AND USES THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-05-22 | — | — | WO | disclosed |