Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ESRRG | P62508 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807953 | 0.85 | ESR1 (0.42) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Bisphenol A SCHEMBL29461417 | 0.81 | ESR1 (0.55) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Phenol SCHEMBL325112 | 0.79 | TSHR (0.43) | ESR1CYP3A4HSD17B10TSHRALDH1A1 | |
| Bisphenol A SCHEMBL9247296 | 0.78 | ESR1 (0.52) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Phenol SCHEMBL15941981 | 0.78 | TSHR (0.42) | ESR1CYP3A4HSD17B10TSHRALDH1A1 | |
| Bisphenol A SCHEMBL21628040 | 0.77 | ESR1 (0.64) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Phenol SCHEMBL15942098 | 0.76 | TSHR (0.41) | ESR1CYP3A4HSD17B10TSHRALDH1A1 | |
| SCHEMBL1825311 | 0.76 | ESR1 (0.53) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Bisphenol A SCHEMBL9280917 | 0.76 | ESR1 (0.76) | ESR1ESR2CYP3A4ESRRGHPGD | |
| Bisphenol A SCHEMBL29411202 | 0.76 | ESR1 (0.76) | ESR1ESR2CYP3A4ESRRGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7858686-B2 | Stabilized polyolefin nanocomposites | POLYONE CORPORATION (US) | 2010-12-28 | — | — | US | claimed |