Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 5/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812673 | 0.86 | GPBAR1 (0.41) | HSD17B1HSD17B2 | |
| SCHEMBL3817235 | 0.85 | HSD17B1 (0.45) | HSD17B1HSD17B2HPGDSMN1; SMN2NPC1 | |
| SCHEMBL3807569 | 0.84 | HSD17B1 (0.45) | HSD17B1HSD17B2MEN1KMT2A | |
| SCHEMBL2158671 | 0.84 | HSD17B1 (0.40) | HSD17B1HSD17B2MAPTMEN1KMT2A | |
| SCHEMBL3816512 | 0.83 | IKBKB (0.39) | HSD17B1HSD17B2GAAMAPTRAB9A | |
| SCHEMBL3817190 | 0.80 | NTRK1 (0.43) | HSD17B1HSD17B2HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3809712 | 0.80 | POLB (0.50) | HSD17B1HSD17B2HTTHPGDNPC1 | |
| SCHEMBL3812250 | 0.80 | HPGD (0.41) | HSD17B1HSD17B2HPGDSMN1; SMN2NPC1 | |
| SCHEMBL3815618 | 0.80 | HSD17B1 (0.47) | HSD17B1HSD17B2NPC1ALDH1A1MAPT | |
| SCHEMBL3807286 | 0.79 | CYP1A2 (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |