Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807569 | 0.88 | HSD17B1 (0.45) | HSD17B1HSD17B2 | |
| SCHEMBL2157987 | 0.86 | HSD17B1 (0.53) | HSD17B1HSD17B2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3816560 | 0.82 | HSD17B1 (0.44) | HSD17B1HSD17B2NPC1RAB9ALMNA | |
| SCHEMBL3817235 | 0.82 | HSD17B1 (0.45) | HSD17B1HSD17B2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3811638 | 0.81 | MAPT (0.45) | HSD17B1HSD17B2L3MBTL1ALDH1A1TUBB4A | |
| SCHEMBL3808987 | 0.80 | HSD17B1 (0.39) | HSD17B1HSD17B2NPC1RAB9AALDH1A1 | |
| SCHEMBL3809473 | 0.79 | HSD17B1 (0.49) | HSD17B1HSD17B2 | |
| SCHEMBL3812250 | 0.79 | HPGD (0.41) | HSD17B1HSD17B2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3809712 | 0.79 | POLB (0.50) | HSD17B1HSD17B2NPC1RAB9AL3MBTL1 | |
| SCHEMBL3816512 | 0.78 | IKBKB (0.39) | HSD17B1HSD17B2RAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |