Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3816423 | 0.82 | SIGMAR1 (0.45) | SIGMAR1ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL3813063 | 0.81 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL6769310 | 0.80 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3817603 | 0.78 | SIGMAR1 (0.43) | SIGMAR1SLC6A2SLC6A4SLC6A3CTNNB1 | |
| SCHEMBL47815 | 0.77 | SIGMAR1 (0.54) | SIGMAR1CTNNB1WNT3AMRGPRX4CYP2A6 | |
| Oxalic Acid SCHEMBL3813466 | 0.77 | KDM4E (0.48) | SIGMAR1ALDH1A1MAPT | |
| SCHEMBL3812050 | 0.75 | SIGMAR1 (0.47) | SIGMAR1GAACYP3A4SLC6A2SLC6A4 | |
| SCHEMBL3807939 | 0.75 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3808261 | 0.75 | SIGMAR1 (0.47) | SIGMAR1SLC6A2SLC6A4SLC6A3CTNNB1 | |
| Oxalic Acid SCHEMBL3807582 | 0.74 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1CTNNB1WNT3AMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |