Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812050 | 0.94 | SIGMAR1 (0.47) | KDM4EATMSIGMAR1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL3811672 | 0.92 | SIGMAR1 (0.45) | KDM4EATMSIGMAR1ALDH1A1 | |
| Oxalic Acid SCHEMBL3813189 | 0.91 | SIGMAR1 (0.44) | KDM4EATMSIGMAR1MEN1KMT2A | |
| Oxalic Acid SCHEMBL3813644 | 0.88 | ACHE (0.48) | KDM4EATMSIGMAR1MEN1KMT2A | |
| Oxalic Acid SCHEMBL3813198 | 0.88 | SIGMAR1 (0.48) | KDM4ESIGMAR1 | |
| Oxalic Acid SCHEMBL3807582 | 0.87 | SIGMAR1 (0.48) | KDM4ESIGMAR1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL3816423 | 0.85 | SIGMAR1 (0.45) | SIGMAR1MEN1KMT2AALDH1A1 | |
| Oxalic Acid SCHEMBL3808414 | 0.85 | SIGMAR1 (0.48) | KDM4ESIGMAR1 | |
| SCHEMBL3812877 | 0.84 | SIGMAR1 (0.46) | KDM4ESIGMAR1ALDH1A1 | |
| Oxalic Acid SCHEMBL3812194 | 0.84 | SIGMAR1 (0.46) | KDM4ESIGMAR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |