Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21647352 | 0.95 | — | — | |
| SCHEMBL21111972 | 0.90 | LMNA (0.32) | LMNA | |
| SCHEMBL18544200 | 0.89 | — | — | |
| SCHEMBL9049422 | 0.87 | CA12 (0.31) | — | |
| SCHEMBL18730166 | 0.86 | LMNA (0.35) | LMNA | |
| SCHEMBL17387531 | 0.86 | LMNA (0.35) | LMNA | |
| SCHEMBL2828097 | 0.86 | LMNA (0.37) | LMNA | |
| Methylamine SCHEMBL18529449 | 0.86 | DNM1 (0.32) | — | |
| SCHEMBL2786134 | 0.83 | CA12 (0.34) | LMNA | |
| SCHEMBL28268084 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090048394-A1 | FAST-CURING MODIFIED SILOXANE COMPOSITIONS | PPG INDUSTRIES OHIO, INC. (US) | 2009-02-19 | — | — | US | disclosed |
| US-7459515-B2 | Fast-curing modified siloxane compositions | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-02 | — | — | US | disclosed |
| US-20060058451-A1 | Fast-curing modified siloxane compositions | AMERON INTERNATIONAL, INC. | 2006-03-16 | — | — | US | disclosed |