Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436967 | 0.87 | ALDH1A1 (0.59) | ALDH1A1HPGDCYP1A2L3MBTL1MEN1 | |
| SCHEMBL4047702 | 0.87 | ALDH1A1 (0.55) | ALDH1A1HPGDCYP1A2MAOAMAOB | |
| SCHEMBL9168588 | 0.85 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP1A2L3MBTL1MEN1 | |
| SCHEMBL249105 | 0.80 | ALDH1A1 (0.52) | ALDH1A1HPGDCYP1A2MAOAKCNJ11 | |
| SCHEMBL11424223 | 0.80 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2MAOAL3MBTL1 | |
| SCHEMBL11323212 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP1A2KCNJ11ATMLMNA | |
| SCHEMBL11022909 | 0.78 | HDAC1 (0.49) | ALDH1A1HPGDCYP1A2KCNJ11MEN1 | |
| SCHEMBL27562738 | 0.78 | HDAC1 (0.49) | ALDH1A1CYP1A2KCNJ11KMT2AHSD17B10 | |
| SCHEMBL2792321 | 0.78 | HDAC1 (0.49) | ALDH1A1CYP1A2KCNJ11KMT2AHSD17B10 | |
| SCHEMBL9187652 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014056852-A1 | LABELED LIGANDS OF THE OXYTOCIN RECEPTOR | UNIVERSITE DE STRASBOURG (FR) | 2014-04-17 | — | — | WO | disclosed |
| WO-2014056852-A1 | LABELED LIGANDS OF THE OXYTOCIN RECEPTOR | UNIVERSITE DE STRASBOURG (FR) | 2014-04-17 | — | — | WO | disclosed |
| US-20110230419-A1 | IAP BINDING COMPOUNDS | NUEVOLUTION A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20090306141-A1 | Novel Compounds | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | disclosed |
| US-7528156-B2 | Compounds | ASTRAZENECA AB (SE) | 2009-05-05 | — | — | US | disclosed |
| CN-1307157-C | Novel compounds | ASTRAZENECA AB (SE) | 2007-03-28 | — | — | CN | disclosed |
| US-6911458-B2 | Compounds | ASTRA ZENECA (SE) | 2005-06-28 | — | — | US | disclosed |
| US-20050090494-A1 | Novel compounds | ASTRAZENECA AB, A SWEDEN CORPORATION | 2005-04-28 | — | — | US | disclosed |
| CN-1476434-A | Novel compounds | — | 2004-02-18 | — | — | CN | disclosed |
| US-20030162772-A1 | Novel compounds | ASTRAZENECA AB (SE) | 2003-08-28 | — | — | US | disclosed |
| EP-1299357-A1 | NOVEL COMPOUNDS | AstraZeneca AB (SE) | 2003-04-09 | — | — | EP | disclosed |
| WO-2001098273-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-12-27 | — | — | WO | disclosed |
| EP-0080355-B2 | Photographic elements containing aryloxy substituted photographic couplers | EASTMAN KODAK CO (US) | 1994-04-06 | — | — | EP | disclosed |
| EP-0080355-B1 | PHOTOGRAPHIC ELEMENTS CONTAINING ARYLOXY SUBSTITUTED PHOTOGRAPHIC COUPLERS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4401752-A | Aryloxy substituted photographic couplers and photographic elements and processes employing same | EASTMAN KODAK COMPANY (US) | 1983-08-30 | — | — | US | disclosed |
| EP-0080355-A1 | Photographic elements containing aryloxy substituted photographic couplers | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1983-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230419-A1 | IAP BINDING COMPOUNDS | BIRC5, BIRC7, BIRC3 | ALDH1A1 2947/4885HPGD 2076/4885CYP1A2 4541/4885 |
| US-20090306141-A1 | Novel Compounds | CHRM2, CHRM1, C1R | ALDH1A1 1779/4885HPGD 4535/4885CYP1A2 345/4885 |
| US-20050090494-A1 | Novel compounds | CHRM2, CHRM1, C1R | ALDH1A1 1779/4885HPGD 4535/4885CYP1A2 345/4885 |
| US-20030162772-A1 | Novel compounds | RPS4X, RPS4Y1, MRPS18A | ALDH1A1 949/4885HPGD 4013/4885CYP1A2 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.