SCHEMBL249105

SCHEMBL249105

CC(=O)Nc1cccc(O)c1NC(C)=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
MAPT P10636 3/20 0.48
POLB P06746 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CYP1A2 P05177 1/20 0.48
KDM4E B2RXH2 4/20 0.46
MAOA P21397 1/20 0.46
APOBEC3A P31941 1/20 0.46
GFER P55789 1/20 0.46
HDAC1 Q13547 1/20 0.46
APOBEC3G Q9HC16 1/20 0.46
CYP2C19 P33261 1/20 0.46
KCNJ11 Q14654 1/20 0.45
GAA P10253 2/20 0.45
KMT2A Q03164 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MEN1 O00255 1/20 0.45
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9400517 0.88 ALDH1A1 (0.44) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL4047702 0.87 ALDH1A1 (0.55) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL6806548 0.83 ALDH1A1 (0.43) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL3785379 0.82 ALDH1A1 (0.50) ALDH1A1HPGDMAPTPOLBCYP1A2
SCHEMBL11323212 0.82 ALDH1A1 (0.47) ALDH1A1MAPTPOLBNPC1RAB9A
SCHEMBL9814086 0.82 ALDH1A1 (0.50) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL19004112 0.82 ALDH1A1 (0.53) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL19181071 0.81 GAA (0.63) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL29375572 0.81 GAA (0.63) ALDH1A1HPGDMAPTPOLBNPC1
SCHEMBL79487 0.81 GAA (0.63) ALDH1A1HPGDMAPTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1339663-B1 NAPHTHALENE DERIVATIVES NOVARTIS AG (CH) 2012-01-04 EP disclosed
EP-2338886-A2 Naphthalene derivatives Novartis AG (CH) 2011-06-29 EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 EP disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 US disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 US disclosed
WO-2005114326-A1 2-HALONAPTHOL COUPLERS EASTMAN KODAK COMPANY (US) 2005-12-01 WO disclosed
CN-1224598-C Naphthalene derivatives NOVARTIS AG (CH) 2005-10-26 CN disclosed
US-20040053890-A1 Naphthalene derivatives NOVARTIS AG (CH) 2004-03-18 US disclosed
CN-1476424-A Naphthalene derivatives ��˹��ŵ�� 2004-02-18 CN disclosed
EP-1339663-A2 NAPHTHALENE DERIVATIVES Novartis AG (CH) 2003-09-03 EP disclosed
WO-2002042248-A2 NAPHTHALENE DERIVATIVES NOVARTIS AG (CH) 2002-05-30 WO disclosed
EP-0778267-A1 SULFONAMIDE DERIVATIVES AND INSECTICIDE, MITICIDE AND NEMATICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-11 EP disclosed
EP-0266326-B1 NOVEL DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS Aktiebolaget Hässle (SE) 1993-03-10 EP disclosed
US-5106862-A DERIVATIVES OF BENZIMIDAZOLES ACTIVE AS ANTI-ULCER AGENTS AKTIEBOLAGET HASSLE (SE) 1992-04-21 US disclosed
EP-0266326-A1 Novel derivatives of benzimidazoles active as anti-ulcer agents Aktiebolaget Hässle (SE) 1988-05-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR ALDH1A1 1045/4885HPGD 1611/4885MAPT 2485/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT ALDH1A1 466/4885HPGD 2662/4885MAPT 3034/4885
US-20040053890-A1 Naphthalene derivatives CYP1A1, SULT1E1, CYP2F1 ALDH1A1 251/4885HPGD 231/4885MAPT 3518/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 ALDH1A1 67/4885HPGD 795/4885MAPT 3518/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH ALDH1A1 1689/4885HPGD 2899/4885MAPT 720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.