SCHEMBL381084

SCHEMBL381084

OC1C=Cc2ccccc2C1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.41
HTR2A P28223 2/20 0.39
HTR6 P50406 1/20 0.38
KDM4E B2RXH2 2/20 0.35
BRD4 O60885 1/20 0.35
CCL2 P13500 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CHRM1 P11229 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
NFKB1 P19838 1/20 0.35
CHRM3 P20309 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2C P28335 1/20 0.35
ADRA1A P35348 1/20 0.35
HRH1 P35367 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14956869 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL30138865 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL2930945 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL639420 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL29741301 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL639419 1.00 CYP2D6 (0.41) CYP2D6HTR2AHTR6KDM4EBRD4
Naphthalene SCHEMBL15752769 0.94 CYP2D6 (0.38) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL12926225 0.83 SIGMAR1 (0.43) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL13998268 0.83 SIGMAR1 (0.43) CYP2D6HTR2AHTR6KDM4EBRD4
SCHEMBL17695459 0.83 SIGMAR1 (0.43) CYP2D6HTR2AHTR6KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4996007-A Catalysis with a group 7 or 8 metal, a quaternary alkyl ammonium bromide cocatalyst and an oxygen activator SHELL OIL COMPANY (US) 1991-02-26 US claimed
US-4982015-A DIHYDRODIHYDROXYNAPHTHALENE SUBSTITUTED WITH ELECTRON WITHDRAWING GROUP SHELL OIL COMPANY (US) 1991-01-01 US claimed
EP-4219735-B1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR ABBOTT DIABETES CARE (US) 2026-04-01 EP disclosed
EP-4538692-A2 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR Abbott Diabetes Care (US) 2025-04-16 EP disclosed
CN-118076602-A Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses 嘉兴优博生物技术有限公司 2024-05-24 CN disclosed
CN-117916215-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2024-04-19 CN disclosed
EP-4219735-A1 METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR Abbott Diabetes Care (US) 2023-08-02 EP disclosed
CN-116472034-A Indene compound, pharmaceutical composition thereof and therapeutic application thereof 藤济(厦门)生物医药科技有限公司 2023-07-21 CN disclosed
CN-115215737-B Method for preparing aldehyde or ketone by alcohol selective oxidation 嘉兴学院 2023-06-27 CN disclosed
CN-116234546-A GPX4 inhibitors, pharmaceutical compositions thereof and their use in the treatment of GPX4 mediated diseases 嘉兴优博生物技术有限公司 2023-06-06 CN disclosed
US-20230159979-A1 TRANSDUCERS, NANOPARTICLE TRANSDUCER DEVICES AND SYSTEMS, AND RELATED METHODS OF USE UNIVERSITY OF WASHINGTON (US) 2023-05-25 US disclosed
EP-0686153-A1 CHEMICAL PROCESS ZENECA LTD (GB) 1995-12-13 EP disclosed
WO-1994019338-A1 CHEMICAL PROCESS ZENECA LIMITED (GB) 1994-09-01 WO disclosed
US-4996007-A Catalysis with a group 7 or 8 metal, a quaternary alkyl ammonium bromide cocatalyst and an oxygen activator SHELL OIL COMPANY (US) 1991-02-26 US disclosed
US-4996007-A Catalysis with a group 7 or 8 metal, a quaternary alkyl ammonium bromide cocatalyst and an oxygen activator SHELL OIL COMPANY (US) 1991-02-26 US disclosed
US-4982015-A DIHYDRODIHYDROXYNAPHTHALENE SUBSTITUTED WITH ELECTRON WITHDRAWING GROUP SHELL OIL COMPANY (US) 1991-01-01 US disclosed
EP-0223890-B1 ARYL DERIVATIVES OF PYRROLE, THEIR OBTENTION AND THEIR USE IN IMMUNOLOGY Albert ROLLAND S.A. Société dite (FR) 1990-11-22 EP disclosed
EP-0223890-A1 Aryl derivatives of pyrrole, their obtention and their use in immunology Albert ROLLAND S.A. Société dite (FR) 1987-06-03 EP disclosed
EP-0076606-B1 BIOCHEMICAL PROCESS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-02-05 EP disclosed
EP-0076606-A1 Biochemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-13 EP disclosed