Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14956869 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL30138865 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL639420 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL29741301 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL381084 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL639419 | 1.00 | CYP2D6 (0.41) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| Naphthalene SCHEMBL15752769 | 0.94 | CYP2D6 (0.38) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL12926225 | 0.83 | SIGMAR1 (0.43) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL13998268 | 0.83 | SIGMAR1 (0.43) | CYP2D6HTR2AHTR6KDM4EBRD4 | |
| SCHEMBL17695459 | 0.83 | SIGMAR1 (0.43) | CYP2D6HTR2AHTR6KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765420-B2 | Method for preparing pterocarpan | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-07-01 | — | — | US | disclosed |
| US-20130130332-A1 | NOVEL METHOD FOR PREPARING PTEROCARPAN | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-05-23 | — | — | US | disclosed |
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | INSTITUTE OF CATALYSIS (CSIC) (ES) | 2012-09-13 | — | — | US | disclosed |
| WO-2010105851-A1 | PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-23 | — | — | WO | disclosed |
| EP-2230312-A1 | Probe compound for detecting and isolating enzymes and means and methods using the same | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2010-09-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120231972-A1 | Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same | SI, GUSB, MPI | CYP2D6 26/4885HTR2A 4649/4885HTR6 2597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.