Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 12/20 | 0.51 |
| ▸ | MGLL | Q99685 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381413 | 0.84 | FAAH (0.60) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381099 | 0.78 | FAAH (0.70) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL12804230 | 0.78 | FAAH (0.76) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381742 | 0.74 | FAAH (0.55) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381172 | 0.70 | FAAH (0.54) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL382462 | 0.68 | FAAH (1.00) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381258 | 0.68 | FAAH (0.47) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381279 | 0.67 | FAAH (0.63) | FAAHMGLLDRD2DRD3KCNH2 | |
| SCHEMBL381681 | 0.67 | FAAH (0.69) | FAAHMGLL | |
| SCHEMBL29262825 | 0.65 | KMT2A (0.56) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408743-A1 | CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105930-A1 | CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-09-23 | — | — | WO | disclosed |