Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 9/20 | 0.70 |
| ▸ | DRD2 | P14416 | 2/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | MGLL | Q99685 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12804230 | 0.95 | FAAH (0.76) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL381279 | 0.84 | FAAH (0.63) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL382462 | 0.82 | FAAH (1.00) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL381098 | 0.78 | FAAH (0.51) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL381413 | 0.77 | FAAH (0.60) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL381742 | 0.73 | FAAH (0.55) | FAAHDRD2DRD3KCNH2MGLL | |
| SCHEMBL14329550 | 0.73 | ALDH1A1 (0.64) | — | |
| SCHEMBL381681 | 0.73 | FAAH (0.69) | FAAHMGLL | |
| SCHEMBL12017703 | 0.71 | FAAH (0.88) | FAAHDRD3MGLL | |
| SCHEMBL10242942 | 0.71 | PTGS2 (0.54) | FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408743-A1 | CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 2012-01-25 | — | — | EP | disclosed |
| WO-2010105930-A1 | CARBAMATE DERIVATIVES IN PARTICULAR FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2010-09-23 | — | — | WO | disclosed |