Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL3423115 | 0.80 | RAD52 (0.53) | RAD52NPSR1TSHR | |
| Glycinebetaine SCHEMBL23528235 | 0.80 | RAD52 (0.53) | RAD52NPSR1TSHR | |
| Glycinebetaine SCHEMBL13736533 | 0.80 | RAD52 (0.53) | RAD52NPSR1TSHR | |
| Glycinebetaine SCHEMBL1245821 | 0.80 | RAD52 (0.53) | RAD52NPSR1TSHR | |
| Glycinebetaine SCHEMBL940799 | 0.79 | BBOX1 (0.34) | TSHR | |
| Glycinebetaine SCHEMBL10425194 | 0.78 | TSHR (0.48) | TSHR | |
| SCHEMBL2302371 | 0.74 | HCAR2 (0.39) | TSHR | |
| Hydrochloric Acid SCHEMBL19899773 | 0.73 | HCAR2 (0.38) | TSHR | |
| Glycinebetaine SCHEMBL22684776 | 0.70 | CHRM1 (0.50) | RAD52NPSR1TSHR | |
| Glycinebetaine SCHEMBL22499790 | 0.68 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1600143-B1 | SKIN PREPARATION FOR EXTERNAL USE CHARACTERIZED BY CONTAINING SUGAR DERIVATIVE OF a,a-TREHALOSE | HAYASHIBARA CO (JP) | 2019-07-10 | — | — | EP | disclosed |
| EP-3143983-A1 | EXTERNAL DERMATOLOGICAL FORMULATION COMPRISING SACCHARIDE DERIVATIVE OF ALPHA, ALPHA-TREHALOSE | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2017-03-22 | — | — | EP | disclosed |
| EP-1731134-B1 | FUNCTIONAL POWDERS | HAYASHIBARA CO (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-8841261-B2 | Functional powdery product | Hayashibara Co., Ltd. (JP) | 2014-09-23 | — | — | US | disclosed |
| US-7854922-B2 | Skin preparation for external use characterized by containing sugar derivative of α, α-trehalose | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2010-12-21 | — | — | US | disclosed |
| US-20070140984-A1 | Functional powdery product | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-06-21 | — | — | US | disclosed |
| US-20070003502-A1 | Skin preparation for external use characterized by containing sugar derivative of alpha, alpha-trehalose | KABUSHIKI KAISHA HAYASHIBARA SEIBUTSU KAGAKU KENKYUJO (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1731134-A1 | FUNCTIONAL POWDERS | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-1600143-A1 | SKIN PREPARATION FOR EXTERNAL USE CHARACTERIZED BY CONTAINING SUGAR DERIVATIVE OF a,a-TREHALOSE | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo (JP) | 2005-11-30 | — | — | EP | disclosed |