Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812574 | 0.94 | KDM4E (0.47) | NPSR1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3817153 | 0.90 | NPSR1 (0.51) | NPSR1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3807312 | 0.88 | NPSR1 (0.53) | NPSR1KDM4EIKBKBRXFP1 | |
| SCHEMBL3811075 | 0.86 | MEN1 (0.48) | NPSR1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3816532 | 0.86 | NPSR1 (0.69) | NPSR1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL3816697 | 0.86 | NPSR1 (0.46) | NPSR1KDM4EMAPTIKBKBLMNA | |
| SCHEMBL3812625 | 0.85 | NPSR1 (0.52) | NPSR1KDM4ERXFP1 | |
| SCHEMBL2157446 | 0.85 | NPSR1 (0.62) | NPSR1KDM4EIKBKBRXFP1 | |
| SCHEMBL3811718 | 0.84 | KCNH2 (0.51) | NPSR1KDM4EIKBKB | |
| SCHEMBL3811663 | 0.82 | NPSR1 (0.48) | NPSR1KDM4EIKBKBALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |