Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812574 | 0.90 | KDM4E (0.47) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL3814765 | 0.89 | MEN1 (0.44) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3817153 | 0.87 | NPSR1 (0.51) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL2158090 | 0.86 | MEN1 (0.50) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3811263 | 0.86 | NPSR1 (0.52) | MEN1MAPTKMT2ALMNAPOLB | |
| SCHEMBL3816884 | 0.82 | MEN1 (0.47) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3807188 | 0.82 | KCNH2 (0.45) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3816563 | 0.82 | NPSR1 (0.54) | MEN1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL3807300 | 0.82 | RELA (0.50) | MEN1KMT2ASMN1; SMN2NFKBIARELA | |
| SCHEMBL3816838 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |