Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812574 | 0.94 | KDM4E (0.47) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3816881 | 0.91 | ALDH1A1 (0.56) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3811263 | 0.90 | NPSR1 (0.52) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3816632 | 0.90 | NPSR1 (0.49) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3812782 | 0.89 | NPSR1 (0.47) | NPSR1KDM4ERXFP1ALDH1A1HPGD | |
| SCHEMBL3812870 | 0.88 | ACLY (0.50) | NPSR1KDM4ERXFP1 | |
| SCHEMBL3811075 | 0.87 | MEN1 (0.48) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3811715 | 0.85 | NPSR1 (0.69) | NPSR1KDM4ERXFP1MEN1KMT2A | |
| SCHEMBL3807904 | 0.85 | HSD17B1 (0.48) | NPSR1KDM4ERXFP1ALDH1A1HPGD | |
| SCHEMBL3815281 | 0.84 | SMN1; SMN2 (0.55) | NPSR1KDM4ERXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |