Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157827 | 0.88 | PTPN1 (0.33) | — | |
| SCHEMBL4147674 | 0.86 | MAPT (0.42) | — | |
| SCHEMBL3809084 | 0.85 | CYP1A2 (0.39) | CYP3A4HPGD | |
| SCHEMBL3815114 | 0.84 | SRD5A2 (0.41) | CYP3A4PPARG | |
| SCHEMBL3817609 | 0.84 | CYP3A4 (0.39) | CYP3A4 | |
| SCHEMBL3813315 | 0.83 | FLT1 (0.39) | CYP3A4 | |
| SCHEMBL3807407 | 0.83 | IKBKB (0.36) | CYP3A4 | |
| SCHEMBL3812137 | 0.82 | AVPR2 (0.42) | CYP3A4 | |
| SCHEMBL3812591 | 0.81 | CYP3A4 (0.32) | CYP3A4SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL3807557 | 0.81 | HSD17B1 (0.40) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |