Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3809084 | 0.88 | CYP1A2 (0.39) | CYP3A4FLT1FLT4KDRTSHR | |
| SCHEMBL2157830 | 0.87 | PTPN1 (0.35) | CYP3A4TSHRCASP1SMN1; SMN2KDM4E | |
| SCHEMBL3812137 | 0.87 | AVPR2 (0.42) | CYP3A4FLT1FLT4KDR | |
| SCHEMBL3817609 | 0.87 | CYP3A4 (0.39) | CYP3A4FLT1FLT4KDRTSHR | |
| SCHEMBL3815114 | 0.87 | SRD5A2 (0.41) | CYP3A4TSHRCASP1SMN1; SMN2KDM4E | |
| SCHEMBL3813315 | 0.86 | FLT1 (0.39) | CYP3A4FLT1FLT4KDRTSHR | |
| SCHEMBL3807407 | 0.86 | IKBKB (0.36) | CYP3A4FLT1FLT4KDRTSHR | |
| SCHEMBL3807557 | 0.83 | HSD17B1 (0.40) | FLT1FLT4KDRTSHRSMN1; SMN2 | |
| SCHEMBL3816864 | 0.81 | FLT1 (0.39) | FLT1FLT4KDRMAPTRAB9A | |
| SCHEMBL3817340 | 0.81 | RORB (0.37) | CYP3A4MAPTMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |