Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | UQCRB | P14927 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816150 | 0.90 | ACLY (0.55) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3816575 | 0.90 | NPSR1 (0.67) | NPSR1KDM4ERXFP1IKBKBMCL1 | |
| SCHEMBL3811715 | 0.87 | NPSR1 (0.69) | NPSR1KDM4ERXFP1IKBKBCA2 | |
| SCHEMBL3807620 | 0.86 | NPSR1 (0.57) | HSD17B2NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3814727 | 0.86 | NPSR1 (0.57) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3815310 | 0.85 | NPSR1 (0.62) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3810994 | 0.84 | NPSR1 (0.55) | NPSR1KDM4ERXFP1IKBKBMCL1 | |
| SCHEMBL2250816 | 0.84 | NPSR1 (0.67) | HSD17B2NPSR1KDM4ERXFP1UQCRB | |
| SCHEMBL3816563 | 0.83 | NPSR1 (0.54) | HSD17B2NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3816898 | 0.83 | ACLY (0.58) | HSD17B2NPSR1KDM4ERXFP1IKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |