Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807336 | 0.92 | DDX3X (0.56) | NPSR1KDM4ERXFP1HPGDL3MBTL1 | |
| SCHEMBL3816575 | 0.89 | NPSR1 (0.67) | NPSR1KDM4ERXFP1IKBKB | |
| SCHEMBL3814765 | 0.87 | MEN1 (0.44) | NPSR1KDM4ERXFP1KMT2AMEN1 | |
| SCHEMBL3811715 | 0.86 | NPSR1 (0.69) | NPSR1KDM4ERXFP1IKBKBCA12 | |
| SCHEMBL3814727 | 0.85 | NPSR1 (0.57) | NPSR1KDM4ERXFP1IKBKBKMT2A | |
| SCHEMBL3807620 | 0.85 | NPSR1 (0.57) | NPSR1KDM4ERXFP1IKBKBHSD17B1 | |
| SCHEMBL3815310 | 0.84 | NPSR1 (0.62) | NPSR1KDM4ERXFP1IKBKBCA12 | |
| SCHEMBL3811277 | 0.84 | PKM (0.53) | NPSR1KDM4ERXFP1L3MBTL1CA2 | |
| SCHEMBL3810994 | 0.83 | NPSR1 (0.55) | NPSR1KDM4ERXFP1IKBKBKMT2A | |
| SCHEMBL3811274 | 0.83 | HSD17B2 (0.56) | NPSR1KDM4ERXFP1IKBKBCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |