Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1431991 | 0.96 | KDM4E (0.50) | KDM4ETDP1GAATRPV6CCR4 | |
| SCHEMBL1431993 | 0.96 | KDM4E (0.50) | KDM4ETDP1GAATRPV6CCR4 | |
| SCHEMBL2578985 | 0.78 | SLC6A4 (0.56) | KDM4ETDP1TRPV6SLC6A4 | |
| SCHEMBL1432717 | 0.78 | RECQL (0.44) | KDM4ETDP1GAASLC6A4ALDH1A1 | |
| SCHEMBL1431665 | 0.78 | FPR2 (0.41) | KDM4ETDP1GAAALDH1A1KMT2A | |
| SCHEMBL1432715 | 0.78 | RECQL (0.44) | KDM4ETDP1GAASLC6A4ALDH1A1 | |
| SCHEMBL1431666 | 0.78 | FPR2 (0.41) | KDM4ETDP1GAAALDH1A1KMT2A | |
| SCHEMBL14862657 | 0.77 | TRPV6 (0.39) | KDM4ETDP1GAATRPV6ALDH1A1 | |
| SCHEMBL29340248 | 0.77 | NPY1R (0.49) | KDM4ETDP1SLC6A4MEN1KMT2A | |
| SCHEMBL1432768 | 0.76 | CA12 (0.52) | KDM4EALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089397-A1 | 5- [4- (AZETIDIN-3-YL0XY) -PHENYL]-2-PHENYL-5H-THIAZ0L0 [5,4-C]PYRIDIN-4-0NE DERIVATIVES AND THEIR USE AS MCH RECEPTOR ANTAGONISTS | Eli Lilly & Company (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008076562-A1 | 5- [4- (AZETIDIN-3-YL0XY) -PHENYL] -2-PHENYL-5H-THIAZ0L0 [5,4-C] PYRIDIN-4-0NE DERIVATIVES AND THEIR USE AS MCH RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |