Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3809931 | 0.98 | SIGMAR1 (0.55) | SIGMAR1KDM4EALDH1A1CYP1A2CYP2A6 | |
| SCHEMBL29546077 | 0.86 | CYP1A2 (0.54) | SIGMAR1KDM4ECYP1A2CYP2A6HRH3 | |
| SCHEMBL869422 | 0.86 | CYP1A2 (0.54) | SIGMAR1KDM4ECYP1A2CYP2A6HRH3 | |
| SCHEMBL3817577 | 0.84 | SIGMAR1 (0.50) | SIGMAR1KDM4ECYP1A2CYP2A6LTA4H | |
| SCHEMBL3808311 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1CYP1A2HRH3 | |
| Hydrochloric Acid SCHEMBL3807771 | 0.83 | RAD52 (0.52) | KDM4EALDH1A1CYP1A2HRH3 | |
| SCHEMBL6246604 | 0.83 | SIGMAR1 (0.68) | SIGMAR1CYP1A2CYP2A6HRH3PYCR1 | |
| SCHEMBL11761176 | 0.81 | KDM4E (0.46) | SIGMAR1KDM4ECYP1A2CYP2A6HRH3 | |
| SCHEMBL11050149 | 0.81 | CYP1A2 (0.55) | SIGMAR1KDM4ECYP1A2CYP2A6HRH3 | |
| Hydrochloric Acid SCHEMBL7211179 | 0.81 | SIGMAR1 (0.66) | SIGMAR1CYP1A2CYP2A6HRH3PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186594-B1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO LTD (JP) | 2009-08-05 | — | — | EP | disclosed |
| US-6797726-B1 | N-alkoxyalkyl-N,N-dialkylamine derivatives or salts thereof, and remedies for nerve degeneration diseases containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 2004-09-28 | — | — | US | disclosed |
| EP-1186594-A1 | N-ALKOXYALKYL-N,N-DIALKYLAMINE DERIVATIVES OR SALTS THEREOF, AND REMEDIES FOR NERVE DEGENERATION DISEASES CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |