Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 4/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.44 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24881522 | 0.88 | KDM1A (0.46) | DAGLAKDM1ANPC1NR1H2NR1H3 | |
| SCHEMBL22036268 | 0.87 | HPGD (0.49) | DAGLAKDM1ANR1H2NR1H3ABHD6 | |
| SCHEMBL27854990 | 0.85 | NR1H2 (0.54) | DAGLAKDM1ANR1H2NR1H3ABHD6 | |
| SCHEMBL698422 | 0.85 | NR1H2 (0.54) | DAGLAKDM1ANR1H2NR1H3ABHD6 | |
| SCHEMBL698218 | 0.85 | NR1H2 (0.54) | DAGLAKDM1ANR1H2NR1H3ABHD6 | |
| SCHEMBL10132334 | 0.84 | NPSR1 (0.50) | NPC1NR1H2NR1H3KMT2A | |
| SCHEMBL5155186 | 0.84 | NPC1 (0.47) | KDM1ANPC1NR1H2NR1H3CHEK2 | |
| SCHEMBL10132250 | 0.83 | CCR3 (0.47) | DAGLANPC1NR1H2NR1H3ABHD6 | |
| SCHEMBL1992473 | 0.83 | FPR3 (0.52) | KDM1ANPC1NR1H2NR1H3ATM | |
| SCHEMBL1992474 | 0.83 | FPR3 (0.52) | KDM1ANPC1NR1H2NR1H3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343760-B1 | MUSCARINIC ANTAGONISTS | SCHERING CORP (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1343760-A2 | MUSCARINIC ANTAGONISTS | Schering Corporation (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6458812-B1 | KIT AND METHOD FOR COGNITION ACTIVATION | SCHERING CORPORATION | 2002-10-01 | — | — | US | disclosed |
| WO-2002051808-A2 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 2002-07-04 | — | — | WO | disclosed |