Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817127 | 0.88 | MEN1 (0.44) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3814627 | 0.88 | MAPT (0.38) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3811133 | 0.87 | LTB4R2 (0.43) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3812584 | 0.86 | SLC6A2 (0.38) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3807275 | 0.86 | CPB1 (0.40) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3816642 | 0.86 | LTB4R2 (0.41) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3809475 | 0.86 | TP53 (0.43) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3812638 | 0.85 | MEN1 (0.40) | ALDH1A1HSD17B10MAPTHPGDRAB9A | |
| SCHEMBL3817094 | 0.84 | CPB1 (0.39) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL3809097 | 0.84 | LTB4R2 (0.41) | ALDH1A1HSD17B10MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |