Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRG | P23470 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814755 | 0.92 | AOC3 (0.40) | LTB4R2AOC3KDM4EMAPTALDH1A1 | |
| SCHEMBL3811133 | 0.91 | LTB4R2 (0.43) | LTB4R2KDM4EMAPTALDH1A1GAA | |
| SCHEMBL3811666 | 0.89 | MEN1 (0.41) | LTB4R2KDM4EMAPTALDH1A1GAA | |
| SCHEMBL3812310 | 0.88 | GRM5 (0.39) | AOC3MAPTALDH1A1RIPK1GAA | |
| SCHEMBL3815202 | 0.88 | HSD17B1 (0.39) | AOC3MAPTRIPK1HSD17B1HSD17B2 | |
| SCHEMBL3807560 | 0.87 | MAPT (0.40) | LTB4R2AOC3MAPTHSD17B1HSD17B2 | |
| SCHEMBL3812473 | 0.87 | PTGES (0.46) | HSD17B1HSD17B2ALOX5 | |
| SCHEMBL3812641 | 0.86 | ALDH1A1 (0.38) | KDM4EMAPTALDH1A1GAAHPGD | |
| SCHEMBL3816633 | 0.86 | LTB4R2 (0.44) | LTB4R2AOC3MAPTPTPRCPTPRG | |
| SCHEMBL3809437 | 0.86 | LTB4R2 (0.42) | LTB4R2KDM4EMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |