Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2157905 | 0.88 | PRMT1 (0.38) | PRMT1ALDH1A1KDM4ECYP3A4RORB | |
| SCHEMBL2158560 | 0.88 | PRMT1 (0.39) | PRMT1CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3812070 | 0.81 | CYP3A4 (0.43) | CYP1A2CYP2C19ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3817340 | 0.80 | RORB (0.37) | CYP1A2CYP2C19ALDH1A1CYP3A4KMT2A | |
| SCHEMBL3809003 | 0.78 | CYP3A4 (0.35) | CYP1A2CYP2C19ALDH1A1CYP3A4HPGD | |
| SCHEMBL14947249 | 0.78 | NR4A1 (0.39) | CYP1A2CYP2C19CYP3A4KMT2AMEN1 | |
| SCHEMBL6319596 | 0.77 | PRMT1 (0.44) | PRMT1CYP1A2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL3811165 | 0.76 | CYP3A4 (0.41) | CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL3811167 | 0.76 | NPC1 (0.34) | CYP1A2CYP2C19ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL3811273 | 0.76 | CYP3A4 (0.39) | CYP1A2CYP2C19ALDH1A1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |