Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORB | Q92753 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3807407 | 0.91 | IKBKB (0.36) | MAPTCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3809084 | 0.91 | CYP1A2 (0.39) | ALDH1A1MAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3807557 | 0.88 | HSD17B1 (0.40) | ALDH1A1LMNAMAPTHTTPOLB | |
| SCHEMBL2158401 | 0.87 | ALDH1A1 (0.41) | RORBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3817609 | 0.86 | CYP3A4 (0.39) | MEN1KMT2AMAPTCYP3A4 | |
| SCHEMBL3815114 | 0.84 | SRD5A2 (0.41) | MAPTHTTPPARGCYP3A4 | |
| SCHEMBL3816864 | 0.84 | FLT1 (0.39) | MEN1KMT2AALDH1A1MAPTCYP1A2 | |
| SCHEMBL3812444 | 0.84 | ALDH1A1 (0.36) | RORBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3814669 | 0.83 | NTRK1 (0.43) | ALDH1A1CYP2C19 | |
| SCHEMBL3813315 | 0.83 | FLT1 (0.39) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |