Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 20/20 | 0.79 |
| ▸ | ADORA2A | P29274 | 20/20 | 0.79 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.79 |
| ▸ | ADORA2B | P29275 | 11/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gw-328267 SCHEMBL13268529 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL1983128 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL1979140 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL1980933 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL13268494 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL1983126 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL4390982 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL29369354 | 0.87 | ADORA2A (1.00) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL5089293 | 0.86 | ADORA2A (0.99) | ADORA3ADORA2AADORA1ADORA2B | |
| Gw-328267 SCHEMBL7228505 | 0.84 | ADORA2A (0.93) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478269-A1 | TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF | Otonomy, Inc. (US) | 2019-05-08 | — | — | EP | disclosed |
| WO-2018005830-A1 | TRIGLYCERIDE OTIC FORMULATIONS AND USES THEREOF | OTONOMY, INC. (US) | 2018-01-04 | — | — | WO | disclosed |
| EP-2490722-A2 | MODULATION OF GEL TEMPERATURE OF POLOXAMER-CONTAINING FORMULATIONS | Otonomy, Inc. (US) | 2012-08-29 | — | — | EP | disclosed |
| EP-2086533-A2 | USE OF AN ADENOSINE ANTAGONIST | Centre de Recherche Publique de la Santé (CRP-Santé) (LU) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008055711-A2 | USE OF AN ADENOSINE ANTAGONIST | CENTRE DE RECHERCHE PUBLIC DE LA SANTE (LU) | 2008-05-15 | — | — | WO | disclosed |