SCHEMBL3813309

SCHEMBL3813309

O=C(O)C1C=CC(Br)(C(=O)O)C=C1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6911631 0.67
SCHEMBL15259687 0.57
SCHEMBL9518312 0.56
SCHEMBL17784048 0.53
SCHEMBL8917182 0.49 EDNRA (0.46)
SCHEMBL28051491 0.49
Benzene SCHEMBL28049392 0.45 CA1 (0.40)
Bicarbonate SCHEMBL28123728 0.45
SCHEMBL23651854 0.45 EDNRA (0.37)
SCHEMBL3482767 0.44 POLB (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101541735-A Process for the synthesis of 2,5-dihydroxyterephthalic acid DU PONT (US) 2009-09-23 CN disclosed
US-7576237-B2 Process for the synthesis of 2,5-Dihydroxyterephthalic acid E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-18 US disclosed
EP-2086918-A1 PROCESS FOR THE SYNTHESIS OF 2,5-DIHYDROXYTEREPHTHALIC ACID E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-08-12 EP disclosed
US-20080177104-A1 PROCESS FOR THE SYNTHESIS OF 2,5-DIHYDROXYTEREPHTHALIC ACID RITTER JOACHIM C 2008-07-24 US disclosed
WO-2008066824-A1 PROCESS FOR THE SYNTHESIS OF 2,5-DIHYDROXYTEREPHTHALIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-05 WO disclosed
US-7355070-B1 Process for the synthesis of 2,5-dihydroxyterephthalic acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-08 US disclosed
EP-0112927-B1 RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-02-11 EP disclosed
US-4632969-A MONO- AND DIFUNCTIONAL ALLYL ESTERS CONTAINING CHLORINE OR BROMINE, IMPACT RESISTANT, GOOD PROCESSABILITY MITSUI TOATSU CHEMICALS, INC. (JP) 1986-12-30 US disclosed
US-4522993-A COPOLYMER HAVING UNITS FROM A BIS-ALLYL HALOGENATED BENZENE DICARBOXYLATE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1985-06-11 US disclosed
EP-0112927-A1 RESIN FOR LENS WITH HIGH REFRACTIVE INDEX AND LENS COMPOSED OF IT MITSUI TOATSU CHEMICALS, Inc. (JP) 1984-07-11 EP disclosed