Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989652 | 0.71 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL10491222 | 0.71 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| SCHEMBL9414032 | 0.71 | GSK3A (0.31) | MGLLHSP90AA1ALDH1A1LMNAPKM | |
| SCHEMBL822300 | 0.71 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| SCHEMBL1955692 | 0.71 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| SCHEMBL670226 | 0.68 | DNMT1 (0.33) | — | |
| SCHEMBL2832318 | 0.67 | MGLL (0.41) | MGLLFAAHHSP90AA1ALDH1A1LMNA | |
| SCHEMBL5138734 | 0.67 | — | — | |
| SCHEMBL4896905 | 0.66 | GSK3A (0.31) | MGLLGSK3AGSK3B | |
| SCHEMBL7800089 | 0.65 | GSK3A (0.44) | MGLLFAAHALDH1A1PKMGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9416383-B2 | Method for enhancing catalytic activity of a lipase | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2016-08-16 | — | — | US | disclosed |
| US-20100330628-A1 | ACTIVATED LIPASES AND METHODS OF USE THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2010-12-30 | — | — | US | disclosed |
| WO-2008134063-A2 | ACTIVATED LIPASES AND METHODS OF USE THEREFOR | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2008-11-06 | — | — | WO | disclosed |