SCHEMBL822300

SCHEMBL822300

C=CC(O)N1C(=O)C=CC1=O

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ GSK3A P49840 1/20 0.31
▸ GSK3B P49841 1/20 0.31
▸ MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL670226 0.73 DNMT1 (0.33) —
SCHEMBL27748204 0.73 MGLL (0.33) GSK3AGSK3BMGLL
SCHEMBL8169087 0.72 MGLL (0.35) GSK3AGSK3BMGLL
SCHEMBL1955692 0.71 GSK3A (0.31) GSK3AGSK3BMGLL
SCHEMBL9414032 0.71 GSK3A (0.31) GSK3AGSK3BMGLL
SCHEMBL3813596 0.71 MGLL (0.32) GSK3AGSK3BMGLL
SCHEMBL8163728 0.71 ALDH1A1 (0.32) —
Hydrochloric Acid SCHEMBL10491222 0.71 GSK3A (0.31) GSK3AGSK3BMGLL
SCHEMBL8989652 0.71 GSK3A (0.31) GSK3AGSK3BMGLL
SCHEMBL3677591 0.71 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107735422-B Aqueous peptide-functionalized polyurethane dispersions 汉高股份有限及两合公司 2020-08-07 — — CN claimed
US-7399816-B2 Maleimidyl-containing material and production method thereof FUJI XEROX CO., LTD. (JP) 2008-07-15 — — US claimed
WO-2007044169-A1 PROCESSES FOR THE PRODUCTION OF HYDROXYALKYLMALEIMIDES ALBEMARLE CORPORATION (US) 2007-04-19 — — WO claimed
US-20060128943-A1 Maleimidyl-containing material and production method thereof FUJI XEROX CO., LTD. 2006-06-15 — — US claimed
US-6589510-B2 For hair-do or hairstyle WELLA AG (DE) 2003-07-08 — — US claimed
US-20020090346-A1 For hair-do or hairstyle Wella GmbH (DE) 2002-07-11 — — US claimed
JP-3012414-A — — None — — JP disclosed
US-11999865-B2 UV curable composition for use in 3D printing BASF SE (DE) 2024-06-04 — — US disclosed
EP-3856856-B1 UV CURABLE COMPOSITION FOR USE IN 3D PRINTING BASF SE (DE) 2024-05-29 — — EP disclosed
US-11897995-B2 Allophanate based dispersing agent BASF SE (DE) 2024-02-13 — — US disclosed
US-11878067-B2 Gel compositions containing copolymer of vinylpyrrolidone and acrylic acid L'OREAL (FR) 2024-01-23 — — US disclosed
EP-4041830-B1 THERMALLY CURABLE TWO-COMPONENT COATING COMPOUNDS BASF SE (DE) 2023-12-06 — — EP disclosed
US-11826963-B2 Active energy ray-curable resin composition and ink for three-dimensional molding support materials KJ CHEMICALS CORPORATION (JP) 2023-11-28 — — US disclosed
CN-1291201-A Water compatible energy curable compositions containing maleimide derivatives SUN CHEMICAL CORP (US) 2001-04-11 — — CN disclosed
EP-0878482-A1 An active energy ray curable composition comprised of a maleimide derivative and a method for curing the said curable composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-11-18 — — EP disclosed
EP-0257586-B1 HYDROXYALKYL- AND AMINOALKYL-FUNCTIONALIZED POLYPHENYLENE ETHERS GENERAL ELECTRIC COMPANY (US) 1992-01-15 — — EP disclosed
JP-H0312414-A CURABLE UNSATURATED IMIDE URETHANE COMPOSITION, ITS PRODUCTION AND CURED MOLDED ARTICLE TEIJIN LTD 1991-01-21 — — JP disclosed
US-4746708-A COMPATIBILIZATION OF BLENDS WITH POLYESTERS GENERAL ELECTRIC COMPANY (US) 1988-05-24 — — US disclosed
EP-0257586-A2 Hydroxyalkyl- and aminoalkyl-functionalized polyphenylene ethers GENERAL ELECTRIC COMPANY (US) 1988-03-02 — — EP disclosed
WO-1987007280-A1 HYDROXYALKYL- AND AMINOALKYL-FUNCTIONALIZED POLYPHENYLENE ETHERS GENERAL ELECTRIC COMPANY (US) 1987-12-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060128943-A1 Maleimidyl-containing material and production method thereof MEN1, VIP, PTMS GSK3A 4444/4885GSK3B 4383/4885MGLL 4158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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