Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27893578 | 0.83 | KDM1A (0.31) | HDAC1HDAC8 | |
| SCHEMBL26436 | 0.82 | DPP4 (0.33) | DPP4 | |
| SCHEMBL27979581 | 0.78 | KDM1A (0.31) | — | |
| SCHEMBL344590 | 0.78 | DPP4 (0.46) | DPP4HDAC1HDAC8MAOB | |
| SCHEMBL30463496 | 0.74 | DPP4 (0.39) | DPP4 | |
| SCHEMBL16404714 | 0.74 | DPP4 (0.39) | DPP4HDAC1HDAC8MAOB | |
| SCHEMBL28156878 | 0.74 | HDAC1 (0.40) | DPP4HDAC1HDAC8MAOB | |
| SCHEMBL29012592 | 0.74 | DPP4 (0.39) | DPP4HDAC1HDAC8MAOB | |
| SCHEMBL30517174 | 0.74 | HDAC1 (0.40) | DPP4HDAC1HDAC8MAOB | |
| SCHEMBL10193862 | 0.74 | DPP4 (0.43) | DPP4HDAC1HDAC8MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023227117-A1 | 3C-LIKE PROTEASE INHIBITOR | 广州国家实验室 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023227118-A1 | 3C-LIKE PROTEASE INHIBITOR | 广州国家实验室 | 2023-11-30 | — | — | WO | disclosed |
| EP-3221318-A1 | FUSED IMIDAZOLE DERIVATIVES AS TGF-BETA INHIBITORS | Rigel Pharmaceuticals, Inc. (US) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016081364-A1 | FUSED IMIDAZOLE DERIVATIVES AS TGF-BETA INHIBITORS | RIGEL PHARMACEUTICALS, INC. (US) | 2016-05-26 | — | — | WO | disclosed |
| EP-2091951-A2 | PYRIDO[2,3-B]PYRAZINE AND[1,8]-NAPHTYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2007130468-A2 | PYRIDO [2, 3-B] PYRAZINE AND [1, 8] -NAPHTHYRIDINE DERIVATIVES AS ALK AND C-MET INHIBITORS | CEPHALON, INC. (US) | 2007-11-15 | — | — | WO | disclosed |