SCHEMBL27979581

SCHEMBL27979581

Fc1cc(Cl)c(CCBr)cc1F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.31
KDM1B Q8NB78 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30030017 0.81 DPP4 (0.33) KDM1AKDM1B
SCHEMBL14774772 0.81 DPP4 (0.33) KDM1AKDM1B
SCHEMBL3814243 0.78 DPP4 (0.39)
SCHEMBL28019097 0.78 KEAP1 (0.39)
SCHEMBL28786022 0.77 KDM1A (0.36) KDM1AKDM1B
SCHEMBL27864489 0.77 PTGES2 (0.37)
SCHEMBL26436 0.76 DPP4 (0.33)
SCHEMBL8894834 0.76
SCHEMBL3121724 0.74 ALDH1A1 (0.40)
SCHEMBL27764905 0.74 SLC6A4 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104039791-A [1,2,3] triazolo [4,5-D ] pyrimidine derivatives as cannabinoid receptor 2 agonists HOFFMANN LA ROCHE 2014-09-10 CN disclosed