SCHEMBL38143

SCHEMBL38143

Nc1ccc(S(=O)(=O)Cl)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.50
IDO1 P14902 2/20 0.43
EP300 Q09472 2/20 0.43
KAT8 Q9H7Z6 2/20 0.43
HDAC3 O15379 1/20 0.43
KAT2B Q92831 1/20 0.43
NCOR2 Q9Y618 1/20 0.43
NSD2 O96028 6/20 0.43
LDHA P00338 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GAA P10253 1/20 0.40
AURKA O14965 1/20 0.40
AURKB Q96GD4 1/20 0.40
CHEK1 O14757 1/20 0.39
NEK2 P51955 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28444885 0.98 TTR (0.48) TTRIDO1EP300KAT8HDAC3
SCHEMBL28977925 0.96 TTR (0.52) TTRIDO1EP300KAT8HDAC3
SCHEMBL28977921 0.94 TTR (0.46) TTRIDO1EP300KAT8HDAC3
Bicarbonate SCHEMBL28267248 0.93 TTR (0.49) TTRIDO1EP300KAT8HDAC3
SCHEMBL6896171 0.91 ALDH1A1 (0.55) TTRIDO1EP300KAT8HDAC3
SCHEMBL7729945 0.89 CA1 (0.53) TTRNSD2ALDH1A1CYP3A4HPGD
SCHEMBL28977927 0.89 TTR (0.46) TTRIDO1EP300KAT8HDAC3
Questiomycin B SCHEMBL28977920 0.88 TTR (0.49) TTRIDO1EP300KAT8HDAC3
SCHEMBL8516378 0.88 TTR (0.66) TTRNSD2ALDH1A1CYP3A4HPGD
SCHEMBL8727652 0.87 TTR (0.47) TTRNSD2ALDH1A1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 37620 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122042871-A Topiramate cleaning chemical residue detection method and kit 广州汉光药业股份有限公司 2026-05-15 CN claimed
EP-4724075-A2 SYSTEMS AND METHODS FOR DETECTION AND QUANTIFICATION OF DOUBLE-STRANDED RNA Promega Corporation (US) 2026-04-15 EP claimed
US-20260069175-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD UNIV MARYLAND (US) 2026-03-12 US claimed
US-12551149-B2 Sample-to-answer diagnostic system for the detection of circulating histones in whole blood UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-17 US claimed
US-12474347-B2 Determination of protein information by recoding amino acid polymers into DNA polymers ABRUS BIO, INC. (US) 2025-11-18 US claimed
EP-4151998-B1 METHOD FOR EVALUATING EFFICACY OF UV-BLOCKING INGREDIENT FOR HAIR P&K SKIN RES CENTER (KR) 2025-09-17 EP claimed
EP-4256347-B1 DETECTION OF AN ANALYTE OF INTEREST BY CROSS SPRAY ESI MASS SPECTROMETRY HOFFMANN LA ROCHE (CH) 2025-07-16 EP claimed
EP-4573372-A2 DETERMINATION OF PROTEIN INFORMATION BY RECODING AMINO ACID POLYMERS INTO DNA POLYMERS Abrus Bio, Inc. (US) 2025-06-25 EP claimed
CN-120195317-A Method for detecting dextromethorphan content in body fluid sample 广州合尔拓生物科技有限公司 2025-06-24 CN claimed
CN-112973482-B Method for dissolving dansyl chloride derivative solution and reagent bottle assembly 上海海洋大学 2025-06-24 CN claimed
US-4387088-A NBD-Acidic phallotoxins and their use in the fluorescence staining of F-actin CORNELL RESEARCH FOUNDATION, INC. (US) 1983-06-07 US claimed
EP-0064551-A4 MONITORING METABOLIC CONTROL IN DIABETIC PATIENTS BY MEASURING GLYCOSYLATED AMINO ACID AND PEPTIDES IN URINE. UNIV ROCKEFELLER (US) 1983-04-06 EP claimed
US-4371374-A Monitoring metabolic control in diabetic patients by measuring glycosylated amino acids and peptides in urine THE ROCKEFELLER UNIVERSITY (US) 1983-02-01 US claimed
EP-0064551-A1 MONITORING METABOLIC CONTROL IN DIABETIC PATIENTS BY MEASURING GLYCOSYLATED AMINO ACID AND PEPTIDES IN URINE. UNIV ROCKEFELLER (US) 1982-11-17 EP claimed
EP-0057236-A1 METHOD FOR DETERMINING TUMOR-ASSOCIATED GLUCOSE SIDE CHAIN, METHOD FOR DIAGNOSING TUMORS, AND KIT FOR DIAGNOSING TUMORS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1982-08-11 EP claimed
WO-1982001804-A1 MONITORING METABOLIC CONTROL IN DIABETIC PATIENTS BY MEASURING GLYCOSYLATED AMINO ACID AND PEPTIDES IN URINE UNIV ROCKEFELLER (US) 1982-05-27 WO claimed
US-4326008-A CROSSLINKED ACRYLIC POLYMERS CONTAINING A FLUORESCENT COMONOMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1982-04-20 US claimed
US-4275300-A Fluorescent composition, a process for synthesizing the fluorescent composition, and methods of use of the fluorescent composition VARIAN ASSOCIATES, INC. (US) 1981-06-23 US claimed
US-4168146-A CHROMOGENS, INDICATORS, FLUORESCENCE AB KABI (SE) 1979-09-18 US claimed
US-4135816-A Method and apparatus for determining the total protein content or individual amino acids GESELLSCHAFT FUR STRAHLEN- UND UMWELTFORSCHUNG MBH (DE) 1979-01-23 US claimed