Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.66 |
| ▸ | NSD2 | O96028 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28977925 | 0.88 | TTR (0.52) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL38143 | 0.88 | TTR (0.50) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL29904571 | 0.87 | CDK2 (0.46) | TTRNSD2ALDH1A1CYP3A4TSHR | |
| SCHEMBL3133065 | 0.87 | CDK2 (0.46) | TTRNSD2ALDH1A1CYP3A4TSHR | |
| SCHEMBL28444885 | 0.86 | TTR (0.48) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7729945 | 0.86 | CA1 (0.53) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL28977921 | 0.82 | TTR (0.46) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL28977927 | 0.82 | TTR (0.46) | TTRNSD2ALDH1A1CYP3A4HPGD | |
| SCHEMBL28977923 | 0.82 | CA2 (0.62) | TTRNSD2TSHRHSD17B10TDP1 | |
| Bicarbonate SCHEMBL28267248 | 0.81 | TTR (0.49) | TTRNSD2ALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112390822-A | Nitric oxide probe and preparation and application thereof | 苏州欣和晟生物科技有限公司 | 2021-02-23 | — | — | CN | disclosed |
| CN-108473723-B | Rubber composition and tire | 株式会社普利司通 | 2020-06-26 | — | — | CN | disclosed |
| CN-108473723-A | Rubber composition and tire | 株式会社普利司通 | 2018-08-31 | — | — | CN | disclosed |
| EP-2457948-B1 | TIRE | BRIDGESTONE CORP (JP) | 2014-10-29 | — | — | EP | disclosed |
| US-8754159-B2 | Tire | BRIDGESTONE CORPORATION (JP) | 2014-06-17 | — | — | US | disclosed |
| US-20120172491-A1 | TIRE | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
| EP-2457948-A1 | TIRE | Bridgestone Corporation (JP) | 2012-05-30 | — | — | EP | disclosed |