Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075203 | 0.99 | ACHE (0.52) | ACHEBCHETSHRUSP2LPAR1 | |
| SCHEMBL3073569 | 0.94 | TSHR (0.50) | ACHEBCHETSHRUSP2LPAR1 | |
| SCHEMBL393311 | 0.85 | TSHR (0.47) | ACHEBCHETSHRLPAR1TDP1 | |
| SCHEMBL393336 | 0.83 | TSHR (0.48) | ACHEBCHETSHRLPAR1TDP1 | |
| SCHEMBL9663990 | 0.81 | ALOX5 (0.58) | ALOX5LTB4R | |
| SCHEMBL18646559 | 0.80 | TSHR (0.62) | ACHEBCHETSHRUSP2LPAR1 | |
| SCHEMBL11830150 | 0.79 | ALOX5 (0.59) | ALOX5ALDH1A1LTB4R | |
| SCHEMBL392054 | 0.79 | TSHR (0.49) | ACHETSHRLPAR1TDP1ALOX5 | |
| SCHEMBL3484433 | 0.79 | TDP1 (0.60) | ACHETSHRUSP2LPAR1TDP1 | |
| SCHEMBL6122069 | 0.78 | TSHR (0.63) | ACHEBCHETSHRUSP2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987026-B1 | AMINOACYL PRODRUG DERIVATIVES AND MEDICAMENTS FOR THE TREATMENT OF THROMBOEMBOLITIC DISORDERS | BAYER HEALTHCARE AG (DE) | 2009-08-26 | — | — | EP | disclosed |
| EP-1987026-A1 | AMINOACYL PRODRUG DERIVATIVES AND MEDICAMENTS FOR THE TREATMENT OF THROMBOEMBOLITIC DISORDERS | Bayer HealthCare AG (DE) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007093328-A1 | AMINOACYL PRODRUG DERIVATIVES AND MEDICAMENTS FOR THE TREATMENT OF THROMBOEMBOLITIC DISORDERS | BAYER HEALTHCARE AG (DE) | 2007-08-23 | — | — | WO | disclosed |